Points - Recent Research
Effectiveness and Cerebral Responses of Multi-Points Acupuncture for Primary Insomnia
  Outcome of Poststroke Cognitive Impairment after Cluster Needling of Scalp Acupuncture Therapy Based on Functional NearInfrared Spectroscopy
  Qiju Dihuang Decoction for Hypertension

Acupuncture Promotes Expression of Hsp84/86 and Delays Brain Ageing in SAMP8 Mice

Chang S1,, et al.

Background
Primary insomnia (PI) is characterized by difficulties in initiating sleep or maintaining sleep, which lead to many serious diseases. Acupuncture for PI has drawn attention with its effectiveness and safety. However, the operation of choosing acupoints lacks scientific suggestion. Our trial aims to provide reference and scientific basis for the selection of acupoints and to explore its possible mechanism.
Methods
A patient-assessor-blinded, randomized and sham controlled trial was designed to compare the efficacy of 5-weeks acupuncture at a single acupoint, the combination of multi-acupoints, and a sham point. The Pittsburgh sleep quality index and Athens Insomnia Scale questionnaire were used for the primary clinical outcomes, while polysomnography was performed for the secondary clinical outcomes. The resting state functional MRI was employed to detect the cerebral responses to acupuncture. The brain activity in resting state was measured by calculating the fractional amplitude of low-frequency fluctuations (fALFF), which reflected the idiopathic activity level of neurons in the resting state. These results were analyzed by two factorial ANOVA test and post-hoc t-tests.
Results
The clinical outcomes suggest that acupuncture could improve clinical symptoms, and the combination of multi-acupoints might lead to a better clinical efficacy. The rs-fMRI results suggested that the brain activity of certain regions was related to the sleep experience, and acupuncture could regulate the activity of these regions. Furthermore, the combination of multi-acupoints could impact more regions which were influenced by the sleep experience.
Conclusions
Acupuncture has been proven to be beneficial for PI patients, and the combination of multi-acupoints might improve its efficacy.

BMC Complement Med Ther. 2020; 20: 254. Published online 2020 Aug 17. doi: 10.1186/s12906-020-02969-6

Source: PubMed

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Outcome of Poststroke Cognitive Impairment after Cluster Needling of Scalp Acupuncture Therapy Based on Functional NearInfrared Spectroscopy

Jing Chen, et al.

Background
Cognitive impairment often arises in patients suffered from stroke. Acupuncture is a recommended treatment option for stroke by the World Health Organization (WHO) and has been shown to improve the cognitive function of patients with poststroke cognitive impairment (PSCI).
Methods
In the present study, we assessed the efficacy of scalp acupuncture with cluster needling on PSCI patients. Fifty six PSCI patients were randomly separated into the reference group who received drug treatment only and the treatment group who received cluster needling of scalp acupuncture on top of drug treatment. Cognitive function was compared between the two groups before and after treatment. We also took the advantage of functional nearinfrared spectroscopy to assess the cerebral hemoglobin levels.
Results
We reveal that applying cluster needling of scalp acupuncture on top of drug treatment can significantly improve the cognitive function and elevate the cerebral hemoglobin levels compared to patients treated with drug only.
Conclusions
Our results suggest that cluster needling of scalp acupuncture is an effective treatment against PSCI and shed light on its application on other neurological disorders.

Brain Behav. 2020 Aug; 10(8): e01731. Published online 2020 Jul 8. doi: 10.1002/brb3.1731

Source: PubMed

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Qiju Dihuang Decoction for Hypertension

Objective
To systematically evaluate the efficacy of Chinese herbal medicine Qiju Dihuang Decoction (QDD) for hypertension.
Methods
A comprehensive literature search of randomized controlled trials using QDD to treat hypertension was conducted in 7 electronic databases, including Chinese databases. Subjects and abstracts of the trials were read in NoteExpress for preliminary screening, and the full text was read for further screening. The data extraction table was made for the selected 19 trials, and risk of bias was assessed by using the Cochrane collaboration tool, followed by data analysis using Rev Man 5.3.
Results
The antihypertensive efficacy of QDD is 1.45 times that of antihypertensive drugs and 1.56 times that of conventional therapies, which can also reduce the endothelin level. QPAD exhibits an antihypertensive effect, and its clinical efficacy is 1.34 times and 1.61 times that of antihypertensive drugs, which can not only significantly lower the diastolic blood pressure but also reduce the 24 h mean ambulate blood pressure. At the same time, it can decrease the TCM syndrome score, inhibit the inflammation, protect the renal function, reduce the insulin resistance, and improve the life quality of patients.
Conclusion
QDD can effectively reduce blood pressure and improve the life quality of patients with hypertension, which plays a certain role in preventing hypertension complications. However, due to the methodological deficiencies, more rigorous randomized controlled trials will be needed in the future to provide stronger evidence.

Evid Based Complement Alternat Med. 2020; 2020: 9403092. Published online 2020 Jul 31. doi: 10.1155/2020/9403092

Source: PubMed

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