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Home > Newsletters > September 2008 > Recent Research

Points - Recent Research

Study on Effects of Different Acupuncture Manipulation Methods at Neiguan (PC 6) on Hand Spasm in Stroke Patient

Effect of Acupuncture at Three Acupoints of Eye on Bellís Palsy

Anti-Acetylcholinesterase Activities of TCM for Treating Alzheimer's Disease


Study on Effects of Different Acupuncture Manipulation Methods at Neiguan (PC 6) on Hand Spasm in Stroke Patient

Wang LC, et al. Department of Neurology, Affiliated Hospital of Integrated Chinese Medicine and Western Medicine of Hebei University of Medical Sciences, Cangzhou 061001, China. wanglichun1976@163.com

OBJECTIVE: To observe therapeutic effects of different needling methods at Neiguan (PC 6) on hand spasm in the patient of stroke. METHODS: One hundred and seventy-two cases were randomly divided into a simple acupuncture group (n=36), a slowly twirling needle group (n = 34), a rapidly twirling needle group (n = 30), a simple lifting-thrusting group (n = 35) and a lifting-thrusting-twirling needle group (n = 37). Acupuncture was given at Neiguan (PC 6), twice each day, 5 min each time, and in combination with rehabilitation exercise. Modified Ashworth scale and Fugl-Meyer (FMA) hand function score were used for assessment of therapeutic effects. RESULTS: The transient effective rate and the effective rate after treatment for 8 weeks for hand spasm were 66.7% and 55.6% in the simple acupuncture group, 82.4% and 85.3% in the slowly twirling needle group, 96.7% and 90.0% in the rapidly twirling needle group, 80.0% and 82.9% in the simple lifting-thrusting group and 94.6% and 91.9% in the lifting-thrusting-twirling needle group, the rapidly twirling needle group and the lifting-thrusting-twirling needle group being better than other 3 groups (P<0.01). After treatment, the grades for Ashworth scale and FMA scores in the lifting-thrusting-twirling needle group and the rapidly twirling needle group were better than those in other 3 groups (P<0.05, P<0.01), with no significant difference between the two groups (P>0.05). CONCLUSION: Acupuncture at Neiguan (PC 6) has a very definite transient effect, and the lifting-thrusting-twirling needling manipulation and the rapidly twirling needling manipulation have the best inhibitive effect on spasm.

Zhongguo Zhen Jiu. 2008 Jul;28(7):503-6.

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Effect of Acupuncture at Three Acupoints of Eye on Bellís Palsy

Zhou CD, et al. Section of Rehabilitation, Guangdong Province Hospital of Integrated Chinese Medicine and Western Medicine, Foshan 528200, China. zcd401@126.com

OBJECTIVE: To probe the effect of acupuncture at three acupoints of eye on Bell palsy. METHODS: Seventy-six cases were randomly divided into a routine acupuncture group and a Yan three needling group, 38 cases in each group. The routine acupuncture group were treated with electroacupuncture (EA) at routinely selected acupoints including Yifeng (TE 17), Dicang (ST 4), etc. and the Yan three needling group were treated by EA at the routinely selected acupoints combined with acupuncture at three acupoints of eye including Jingming (BL 1), Shangming, Chengqi (ST 1). The intensity on 0.05 ms in the intensity/time (I/t) curve for frontal ventral fronto-occipital muscle and orbicular muscle of mouth at the affected side was used for assessment criteria of course of disease, and frontal ventral fronto-occipital muscle restoring the raising eyebrow action and orbicular muscle of mouth restoring to House-Brackmann grade I and II were regarded as the therapeutic time limit. RESULTS: Routine EA treatment combined with acupuncture at the 3 acupoints of eye could significantly increase clinical therapeutic effect on Bell palsy with a cured rate of 89.5%, which was better than 65.8% in the routine acupuncture group (P<0.05), and the therapeutic cycle was shorted. CONCLUSION: Acupuncture at the 3 acupoints of eye can significantly improve Bell palsy and promote recovery of functions of facial nerves.

Zhongguo Zhen Jiu. 2008 Jul;28(7):489-91.

Source: PubMed

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Anti-Acetylcholinesterase Activities of TCM for Treating Alzheimer's Disease

Lin HQ, et al. Department of Biochemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, SAR, China.

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive memory loss and cognitive impairment. It is the most common type of dementia in the ageing population due to a severe loss of cholinergic neurons in selected brain area. At present, acetylcholinesterase inhibitors (AChEI) are the first group of drugs approved by the FDA to treat mild to moderate Alzheimer's disease. Most of these drugs such as huperzine and galanthamine are originally isolated from plants. In this study, the AChE inhibitory activities from extracts of Chinese medicinal herbs that have traditionally been prescribed to treat insomnia and brain function disorders were examined in a 96-well plate assay based on Ellman's method. Both ethanol and aqueous extracts of 26 traditional Chinese medicinal herbs were tested. Inhibitory effects were expressed as the percentage of inhibition. For the herbal extracts that were shown to exert a significant inhibition, dose-dependent inhibitory assays were also performed. Ethanol and aqueous extracts of six herbs were found to have high AChE inhibitory activities in a dose-dependent manner. The IC(50) of these herbal extracts on inhibition of AChE are at around 5-85mum/ml. The results of this study indicate that there is a great potential to search for novel usage of these medicinal herbs for the treatment of AD.

Chem Biol Interact. 2008 Jun 23.

Source: PubMed

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