and Moxibustion Treatment of Chronic Atrophic Gastritis
Gao X, et al. Department of Acupuncture and Moxibustion, Henan
College of Traditional Chinese Medicine, Zhengzhou 450008, China.
OBJECTIVE: To observe the clinical therapeutic effects of acupuncture and
moxibustion in treating chronic atrophic gastritis. METHODS: Patients who met
the criteria were randomly divided into the treatment groups consisting of the
acupuncture group (30 cases) and the acupuncture-moxibustion group (30 cases),
and the control group (28 cases). After two months of treatment, observed were
safety and the curative effects, through general physical check ups, routine
examinations of blood, urine and feces, and symptoms, pathology and gastrin
before, during and after the treatment. RESULTS: (1) The treatment groups showed
significant superiorities in the improvement of symptoms, with the
acupuncture-moxibustion group showing the best therapeutic effects. (2) The
acupuncture-moxibustion group showed marked differences before and after the
treatment in the improvement of glandular atrophy and intestinal metaplasia,
with a total effective rate of 66.67%. (3) After the treatment, the three groups
all showed marked improvement in the level of serum gastrin, with the
acupuncture-moxibustion group showing the best effects. CONCLUSION: Acupuncture
and moxibustion have definite therapeutic effects for chronic atrophic
gastritis, especially in improving the symptoms. Acupuncture or acupuncture
combined with moxibustion can provide possibilities in reversing the pathologic
changes of glandular atrophy and intestinal metaplasia for patients with chronic
atrophic gastritis. Acupuncture-moxibustion is really an effective and safe
therapy for chronic atrophic gastritis.
J Tradit Chin Med. 2007 Jun; 27(2):87-91.
Acupuncture Compared with Other Acupuncture for Treatment of Chronic Neck Pain
Itoh K, et al. Department of Clinical Acupuncture and
Moxibustion, Meiji University of Oriental Medicine, Kyoto 629-0392, Japan.
INTRODUCTION: There is some evidence for the efficacy of acupuncture in chronic
neck pain (CNP) treatment, but it remains unclear which acupuncture modes are
most effective. Objective was to evaluate the effects of trigger point
acupuncture on pain and quality of life (QOL) in CNP patients compared to three
other acupuncture treatments (acupoints, non-trigger point and sham treatment).
METHODS: Forty out-patients (29 women, 11 men; age range: 47-80 years) from the
Department of Orthopaedic Surgery, Meiji University of Oriental Medicine, with
non-radiating CNP for at least 6 months and normal neurological examination were
randomised to one of four groups over 13 weeks. Each group received two phases
of acupuncture treatment with an interval between them. The acupoint group
(standard acupuncture; SA, n=10) received treatment at traditional acupoints for
neck pain, the trigger point (TrP, n=10) and non-trigger point (non-TrP, n=10)
groups received treatment at tenderness points for the same muscle, while the
other acupuncture group received sham treatments on the trigger point (SH,
n=10). Outcome measures were pain intensity (visual analogue scale; VAS 0-100mm)
and disease specific questionnaire (neck disability index; NDI, 60-point scale).
RESULTS: After treatment, the TrP group reported less pain intensity and
improved QOL compared to the SA or non-TrP group. There was significant
reduction in pain intensity between the treatment and the interval for the TrP
group (p<0.01, Dunnett's multiple test), but not for the SA or non-TrP group.
CONCLUSION: These results suggest that trigger point acupuncture therapy may be
more effective on chronic neck pain in aged patients than the standard
Complement Ther Med. 2007 Sep;15(3):172-9. Epub 2006 Jul 10.
Oridonin (Dong Ling Cao) on Proliferation of HT29 Human Colon Carcinoma Cell
Lines both in Vitro and in Vivo in Mice
Zhu Y, et al. Department of Biological Science and
Biotechnology, Tsinghua University, Beijing, China.
Oridonin, an active ditepenoid component isolated from Rabdosia rubescens which
is currently one of the most important Chinese traditional herbs, has been
reported to exhibit anti-tumor effects in vitro. In this study, the
anti-proliferation effect of oridonin against the human colorectal carcinoma
cells HT29 was investigated both in vitro and in vivo. MTT assay showed that
oridonin inhibited HT29 cells in a time- and dose-dependent manner. Flow
cytometric analysis demonstrated that oridonin induced a G2/M phase arrest.
Apoptotic bodies were observed by Hoechst 32258 fluorescence staining. Notable
apoptosis and decrease of mitochondrial membrane potentials was also detected by
flow cytometry. In the in vivo experiments, oridonin (10, 15, 20 mg kg(-1) of
body weight, on days 1-12) was injected intraperitoneally into mice 24 h after
the mice were incubated with HT29 cells. Inhibition of the solid tumor was
observed. As a result, oridonin could inhibit the proliferation of HT29 cells
both in vitro and in vivo, and induce apoptosis partly via the mitochondrial
Pharmazie. 2007 Jun;62(6):439-44