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Home > Newsletters > November 2006 > Recent Research

Points - Recent Research

Effects of Acupuncture for Dispersing Fei, Invigorating Pi and Reinforcing Shen on Heart Rate Variability and Pulmonary Function in Bronchial Asthma Patients

Acupuncture for Treatment of Irritable Bowel Syndrome

Study on Angiogenesis Activity of Danggui, Chuanxiong and Danshen

Effects of Acupuncture for Dispersing Fei, Invigorating Pi and Reinforcing Shen on Heart Rate Variability and Pulmonary Function in Bronchial Asthma Patients

Zhang WP. , et al. China Academy of Chinese Medical Sciences, Beijing.

OBJECTIVE: To explore the acting mechanism of acupuncture treatment for dispersing Fei, invigorating Pi and reinforcing Shen (DFIPRS) on bronchial asthma. METHODS: Seventy-one chronic asthma patients in persistent or remission period were randomly assigned to two groups with stratified method, the treated group (40 cases) and the control group (31 cases). Anti-asthmatic medicine were given to both groups and acupuncture therapy to the treated group additionally on the acupoints for DFIPRS including Quchi (Lt11), Lieque (LU7), Yuji (Lu10), Neiguan (P6), Zusanli (ST36), Sanyinjiao (Sp6) and Taixi (K13) using uniform reinforcing-reducing manipulation. The changes of heart rate variability (HRV) frequency-domain index and the pulmonary function were observed before and after treatment, and the immediate effect before and after the first needling of acupuncture was also observed in 17 patients. RESULTS: After acupuncture treatment, the indices of pulmonary function improved significantly and the function of vegetative nervous system, showed by HRV, were also elevated in the treated group (P < 0.05 or P < 0.01) and significantly superior to that in the control group after treatment (P < 0.05 or P < 0.01 ). CONCLUSION: Acupuncture therapy could significantly improve pulmonary function of asthma patients, its mechanism may be related to the regulation of vegetative nerve function.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Sep;26(9):799-802.

Source PubMed


Acupuncture for Treatment of Irritable Bowel Syndrome

Lim B, et al. University of Maryland School of Medicine, Center for Integrative Medicine, Kernan Hospital Mansion, 2200 Kernan Drive, Baltimore, Maryland 21207-6697, USA.

BACKGROUND: Irritable bowel syndrome (IBS), a disorder of altered bowel habits associated with abdominal pain or discomfort. The pain, discomfort, and impairment from IBS often lead to healthcare medical consultation (Talley 1997) and workplace absenteeism, and associated economic costs (Leong 2003). A recent randomized controlled trial shows variable results but no clear evidence in support of acupuncture as an effective treatment for IBS (Fireman 2001). OBJECTIVES: The objective of this systematic review is to determine whether acupuncture is more effective than no treatment, more effective than 'sham' (placebo) acupuncture, and as effective as other interventions used to treat irritable bowel syndrome. Adverse events associated with acupuncture were also assessed. SEARCH STRATEGY: The following electronic bibliographic databases were searched irrespective of language, date of publication, and publication status: MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL) on The Cochrane Library, EMBASE, the Chinese Biomedical Database, the Cumulative Index to Nursing and Allied Health (CINAHL), and the Allied and Complementary Medicine Database (AMED). References in relevant reviews and RCTs were screened by hand. The last date for searching for studies was 7 February 2006. SELECTION CRITERIA: Published reports of randomized controlled trials (RCTs) and quasi-randomised trials of acupuncture therapy for IBS. DATA COLLECTION AND ANALYSIS: All eligible records identified were dually evaluated for eligibility and dually abstracted. Methodological quality was assessed using the Jadad scale and the Linde Internal Validity Scale. Data from individual trials were combined for meta-analysis when the interventions were sufficiently similar. Heterogeneity was assessed using the I squared statistic. MAIN RESULTS: Six trials were included. The proportion of responders, as assessed by either the global symptom score or the patient-determined treatment success rate, did not show a significant difference between the acupuncture and the sham acupuncture group with a pooled relative risk of 1.28 (95% CI 0.83 to 1.98; n=109). Acupuncture treatment was also not significantly more effective than sham acupuncture for overall general well-being, individual symptoms (e.g., abdominal pain, defecation difficulties, diarrhea, and bloating), the number of improved patients assessed by blinded clinician, or the EuroQol score. For two of the studies without a sham control, acupuncture was more effective than control treatment for the improvement of symptoms: acupuncture versus herbal medication with a RR of 1.14(95% CI 1.00 to 1.31; n=132); acupuncture plus psychotherapy versus psychotherapy alone with a RR of 1.20 (95% CI 1.03 to 1.39; n=100). When the effect of ear acupuncture treatment was compared to an unclearly specified combination of one or more of the drugs diazepam, perphenazine or domperidone, the difference was not statistically significant with a RR of 1.49(95% CI 0.94 to 2.34; n=48). AUTHORS' CONCLUSIONS: Most of the trials included in this review were of poor quality and were heterogeneous in terms of interventions, controls, and outcomes measured. With the exception of one outcome in common between two trials, data were not combined. Therefore, it is still inconclusive whether acupuncture is more effective than sham acupuncture or other interventions for treating IBS.

Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005111

Source: PubMed


Study on Angiogenesis Activity of Danggui, Chuanxiong and Danshen

Meng H, et al. Department of Physiology, Xi Jing Hospital, China.

OBJECTIVE: To observe the effect of danggui (Radix angelicae sinensis), chuanxiong (Rhizoma chuanxiong) and danshen (Radix salvae miltionrrhizae) on cardiac microvascular endothelial cells (CMECs) obtained from rat and quantitation of vessels on chick embryo chorioallantoic membrane (CAM) model. METHODS: Normal rat cardiac microvascular endothelial cells (CMECs) were cultured by collagenase and trypsin and the influences of the herbs on the CMECs were observed by cell count and MTT colorimetry. The activity of blood vessels was determined by quantitation of vessels on chick embryo chorioallantoic membrane (CAM) model. RESULTS: Compared with the normal group, after treatment with chuanxiong of high dosage, danggui of high and middle dosages, danshen of high and middle and low dosages, they enhanced proliferation significantly (P < 0.05). The two later could be in dependent dose. And the herbs might increase quantitation of vessels on CAM. CONCLUSION: These Chinese herbs may promote angiogenesis by stimulating proliferation of CMEC and increasing blood vessels.

Zhong Yao Cai. 2006 Jun;29(6):574-6

Source: PubMed


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