The Effect of Chinese herbs on the
Expression of Aquaporin
3,4 Gene in Gastric Mucosa of Patients with Pi-Wei
Chen GX, et al. Guangdong Provincial Hospital of Traditional
Chinese Medicine, Guangzhou. email@example.com
A study was conducted to examine the relationship between Pi-Wei
Damp-Heat Syndrome (PWDHS) with expression of aquaporin (AQP) 3,4 gene in
gastric mucosa and the effects of Qingre Huashi Recipe (QHR) on the expression.
A total of 68 patients with chronic superficial gastritis were differentiated
into Pi-Wei Damp-Heat Syndrome group (PWDHS, n = 53, 19 cases with predominant
Dampness, 14 cases with predominant Heat, 20 cases with Dampness equal to Heat)
and Pi deficiency Syndrome group (PDS, n = 15). The PWDHS group was treated with
QHR. The expression of AQP 3,4 gene in the two groups were verified by
fluorescence quantitative polymerase chain reaction (FQ-PCR). The results of the
study showed that expression of AQP 3 gene in PWDHS was higher than that in PDS
and the healthy group, but the difference showed no statistical significance.
Expression of AQP 4 gene in PWDHS was obvious higher than that in PDS and the
healthy group (P <0.05 or P <0.01), but the difference of AQP 4 gene expression
between PDS and the healthy group was insignificant. Comparison among various
sub-types of PWDHS showed that the AQP 4 gene expression in the predominant
dampness > dampness equal to heat> predominant heat. AQP 3,4 gene expression in
PWDHS was significantly decreased after QHR treatment, especially in the cases
with predominant dampness syndrome (P <0.01), approaching that in the healthy
group and PDS. In conclusion, abnormal expression of AQP 3,4 gene may be one of
the possible mechanisms of PWDHS pathogenesis, and Chinese herbs could influence
AQP 3,4 gene expression to play a key role in treatment.
Acupuncture Pain Management for
Patients with Cystic Fibrosis
Lin YC, et al. Medical
Acupuncture Service, Department of Anesthesiology Perioperative and Pain
Medicine, Children's Hospital Boston Harvard Medical School, Boston,
Massachusetts 02115, USA.
According the authors of the study, cystic fibrosis (CF) is
the most commonly occurring genetic disorder among Caucasians. The purpose of
this study was to determine the effects of acupuncture for pain management in
patients with CF; clinical data was obtained regarding the integration of
acupuncture into the management of pain in patients with CF. Pain was measured
using visual analog scales. It was found that acupuncture was effective in
decreasing pain complaints in patients with CF. No side effects or complications
were reported in relation to the acupuncture treatment. Acupuncture is effective
for managing symptoms and illnesses associated with CF. Further randomized
controlled trials will be necessary to evaluate additional efficacy in pain
management and the improvement of the quality of life of patients with CF.
Effects of Laser Acupuncture on Chronic Tension Headache
Ebneshahidi NS, et al. Physical Therapy Dept, Isfahan
University of Medical Sciences, Isfahan, Iran.
A recent study was done to examine the effects of laser
acupuncture on chronic tension headaches. Fifty patients were randomly placed in
two groups – treatment and placebo. The treatment group received low energy
laser acupuncture to LU7, LI4, GB14, and GB20 bilaterally. Points were
irradiated for 43 seconds, and the intensity was 1.3J (approximately 13J/cm2). A
total of ten sessions were given, three times per week. The placebo group was
treated in a similar way except that the levels of intensity was set to zero.
The outcome variables were headache intensity (VAS), duration of attacks, and
number of days with a headache per month, by daily diary, assessed monthly to
three months after treatment. The results showed that there were significant
differences between the groups (P<0.001) in changes from baseline in months one,
two and three, in median score for headache intensity (treatment group -5, -3
and -2, placebo group -1, 0 and 0), median duration of attacks (treatment group
-6, -4 and -4, placebo group -1, 0 and 0 hours), and median number of days with
headache per month (treatment group -15, -10 and -8, placebo group -2, 0 and 0).
In conclusion, this study suggests that laser acupuncture may be an effective
treatment for chronic tension-type headache, but the results should be confirmed
in larger and more rigorous trials.