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Home > Newsletters > March 2006 > Recent Research

Points - Recent Research

Effect of Acupuncture at Sanyinjiao (SP 6) on Glucose Metabolism in a Patient with Dysmenorrhea

The Treatment of Obesity by Acupuncture

Cosmetic Applications of Selected Traditional Chinese Herbal Medicines


Effect of Acupuncture at Sanyinjiao (SP 6) on Glucose Metabolism in a Patient with Dysmenorrhea

Gong P, et al. Institute of Integrated Traditional Chinese & Western Medicine, The Affiliated Tongji Hospital of Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China.

The purpose of this study is to investigate the central modulating mechanism of acupuncture at Sanyinjiao (SP 6) in treatment of primary dysmenorrhea. 18F-FDG positron emission tomograph imaging of whole brain was performed in six patients with primary dysmenorrhea during two stimulation: pseudo acupuncture and real acupuncture at Sanyinjiao (SP 6). The areas of cerebral glycometabolism change were obtained by using statistical parametric mapping (SPM). Meanwhile the pain intensity before and after pseudo-acupuncture and real acupuncture was assessed with 0-10 numerical pain intensity scale. No differences in the values of pain before and after pseudo-acupuncture (P > 0.05). The value of pain after acupuncture was significantly lower than that before acupuncture (P < 0.01). Most of the activated brain areas were shared with the areas activated by pain as described in the literature. The brain areas of increasing glycometabolism were ipsilateral lentiformn nucleus (globus pallidus, putamen), cerebellum and insula, bilateral thalamus, ipsilateral paracentral lobule, bilateral amygdala, contralateral midbrain, bilateral second somatosensory cortex, ipsilateral hippocampus and anterior cingulate, contralateral mammillary body. The brain areas of decreasing glycometabolism were limited in small cerebral cortex.

Acupuncture at Sanyinjiao (SP 6) can relieve significantly the pain of the patient. Primary dysmenorrhea is cured mainly by activating the area involved in pain. It is indicated that acupuncture can relieve pain and balancing the pain-related central networks. Also neuroendocrine may play a role in the therapy.

Zhongguo Zhen Jiu. 2006 Jan;26(1):51-5. Related Articles, Links

Source PubMed


The Treatment of Obesity by Acupuncture

Cabyoglu MT, et al. Department of Physiology, Selcuk University, Faculty of Meram Medical, Konya, Turkey. tugcab@yahoo.com

The present study is an investigation of the results of the studies on the effects of acupuncture application therapy on obesity. It has been reported that acupuncture application in obesity treatment is effective in procuring weight loss. It can affect appetite, intestinal motility, and metabolism, as well as emotional factors such as stress. Increases in neural activity in the ventromedial nuclei of the hypothalamus, in tone in the smooth muscle of the stomach and in levels of enkephalin, beta endorphin, and serotonin in plasma and brain tissue have also been observed with the application of acupuncture. It has been observed that acupuncture application to obese people increases excitability of the satiety center in the ventromedial nuclei of the hypothalamus. Acupuncture stimulates the auricular branch of the vagal nerve and raises serotonin levels. Both of these activities have been shown to increase tone in the smooth muscle of the stomach, thus suppressing appetite. Among other things, serotonin enhances intestinal motility. It also controls stress and depression via endorphin and dopamine production. In addition to these effects, it is thought that the increase in plasma levels of beta endorphin after acupuncture application can contribute to the body weight loss in obese people by mobilizing the body energy depots through lipolithic effect.

Int J Neurosci. 2006 Feb;116(2):165-75. Related Articles, Links

Source: PubMed


Cosmetic Applications of Selected Traditional Chinese Herbal Medicines

Wang KH, et al. Department of Dermatology, Taipei Medical University Hospital, Taipei 110, Taiwan; Department of Dermatology, Taipei Municipal Wan-Fang Hospital, Taipei 116, Taiwan.

Because tyrosinase catalyzes melanin synthesis, tyrosinase inhibitors are important in cosmetic skin-whitening. Oxidative stress contributes to skin aging and can adversely affect skin health, which means antioxidants active in skin cells may support skin health. We examined 25 traditional Chinese herbal medicines that might be useful for skin-whitening and skin health. Extracts (100mug/mL) were tested for cytotoxicity on human epidermal melanocytes (HEMn); 12 exhibited low cytotoxicity. Their effects on tyrosinase and melanin inhibitory activities and free radical scavenging activities were further assessed. Phenolic contents were evaluated using Folin-Ciocalteu reagent. Four herbs, Pharbitis nil, Sophora japonica, Spatholobus suberectus, and Morus alba, exhibited potent inhibitory effects on tyrosinase (IC(50) values 24.9, 95.6, 83.9, and 78.3mug/mL, respectively). Melanin inhibition was not dose-dependent. Sophora japonica (IC(50): 14.46mug/mL, 1,1-diphenyl-2-picrylhydrazyl (DPPH); 1.95mug/mL, hydroxyl radical) and Spatholobus suberectus (IC(50): 10.51mug/mL, DPPH; 4.36mug/mL, hydroxyl radical) showed good antioxidative activities and high phenolic contents (255 and 189mg of gallic acid/g extract, respectively). Among active anti-tyrosinase extracts, Sophora japonica and Spatholobus suberectus were especially potent in HEMn cells in terms of free radical scavenging effects and high phenolic contents, making them the strongest candidates for cosmetic application found in the current study.

J Ethnopharmacol. 2006 Feb 21; [Epub ahead of print] Related Articles, Links

Source: PubMed
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This Month's Articles

March 2006
Volume 4, Number 3

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How Much Do You Know About Your Pulse?

Recent Research

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