Electroacupuncture for Strengthening Gastrointestinal
Motility in the Rat with Acute Pancreatitis
Li J, et al. Department of Acupuncture, First
Clinical College of Harbin Medical University, Harbin 150001, China. hydyylj@163.com
OBJECTIVE: To explore the mechanism of EA in treatment of acute pancreatitis.
METHODS: Twenty-four healthy male Wistar rats were randomly divided into 3
groups, a control group, a model group and an EA group. In the model group, rat
acute pancreatitis model was prearpared by intraperitoneal injection of
Caerulein, and in the EA group, EA was given at "Zusanli" (ST 36) and "Tianshu"
(ST 25) of the model rat. The gastric emptying rate, small intestinal impelling
ratio, myeloperoxidase activity in the pancreas tissue, pathological score of
the pancreas and serum amylase were detected. RESULTS: Compared with the control
group, both the gastric emptying rate and the intestinal impelling ratio
significantly decreased in the model group (P<0.05), and they significantly
increased in the EA group compared with the model group (P<0.05).
Myeloperoxidase activity in the pancreas tissue, pathological score of the
pancreas and serum amylase activity significantly decreased in the EA group as
compared with the model group (P<0.05). CONCLUSION: EA can significantly improve
the disturbance of gastrointestinal motility induced by acute pancreatitis and
relieve pathological damage of pancreas.
Zhongguo Zhen Jiu. 2008 May;28(5):365-8
Source PubMed
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Parasitic Loranthus from Loranthaceae Rather than Viscaceae
Potently Inhibits Fatty Acid Synthase and Reduces Body Weight in Mice
Wang Y, et al.College of Life Science, Graduate
University of Chinese Academy of Sciences, P.O. Box 3908, Beijing 100049, China.
AIM OF THE STUDY: Our previous results have shown one species of parasitic
loranthus (Taxillus chinensis (DC.) Dancer) exhibits potent inhibition on fatty
acid synthase (FAS) that is proposed to be a potential therapeutic target for
treatment of obesity. However, the medicinal parasitic loranthus come from tens
of plants of two families, the Loranthaceae and the Viscaceae. This study was
carried out to figure out whether these parasitic loranthus from the two
families have similar inhibitory ability on FAS, and whether the parasitic
loranthus with potent inhibitory ability on FAS significantly reduce body weight
of animal. MATERIALS AND METHODS: CD-1 mice were used to test the effects of
samples on their body weight and food intake in 20 days. The reversible and
irreversible inhibition on FAS was assayed to study the inhibitory ability of
sixteen different medicinal plants from these two families, which were collected
in nature. RESULTS: The reversible inhibitory ability of the extracts from the
Loranthaceae was nearly 400-fold stronger than that from the Viscaceae. The
species from the genus Taxillus Tieghem showed the best effect on FAS in both
reversible and irreversible inhibition. Moreover, the difference in host plants
did not affect markedly on the inhibitory ability of parasitic loranthus. The
medicinal herb with high inhibitory ability on FAS significantly reduced the
body weight and food intake of mice by oral administration. CONCLUSIONS: The
medicinal herbs from the family Loranthaceae, rather than those from the family
Viscaceae, should be suitable to apply as botanical sources of parasitic
loranthus for weight control. The herbs from genus Taxillus Tieghem are the
best.
J Ethnopharmacol. 2008 May 23.
Source: PubMed
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Chinese Herbal Medicine for Premenstrual Syndrome
Chou PB, et al. School of Biomedical and Clinical
Sciences, Victoria University, Australia.
Premenstrual syndrome (PMS) is a common disorder troubling many women during
their reproductive years. The Chinese have been using herbal medicines to treat
menstrual cycle related symptoms for centuries. The present study examined the
effectiveness of Chinese herbal medicine for the treatment of PMS among
Australian women within the theoretical framework of traditional Chinese
medicine (TCM). Sixty-one women were assigned randomly into two groups within
different TCM patterns. Herbal medicine and placebo were provided sequentially
for a period of three months. There were significant differences (p < 0.01) in
scores after three months of treatment between Chinese herbal medicine and
placebo in premenstrual physical and psychological symptoms, depression, anxiety
and anger favoring herbal medicine, but with no difference in perceived stress
(p > 0.05). There were highly significant reductions (p < 0.001) between
baseline and the end of the third herbal treatment month in all assessments in
both groups except that a significant result (p < 0.05) was recorded on
perceived stress only in the herbs-first group. No adverse effects were reported
by any participant. The results support the hypothesis that the symptoms
occurrence and severity of PMS can be effectively reduced by the use of Chinese
herbal medicine.
J Psychosom Obstet Gynaecol. 2008 Feb 5:1-8.
Source: PubMed [TOP] |