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Home > Newsletters > August 2007 > Recent Research

Points - Recent Research

Acupuncture as a Potential Treatment for Non-Cardiac Chest Pain 

Two Styles of Acupuncture for Treating Painful Diabetic Neuropathy

Investigation of the Effects of Chinese Medicine on Fibroblast Viability: Implications in Wound Healing

Acupuncture as a Potential Treatment for Non-Cardiac Chest Pain

Macpherson H, Dumville JC.

OBJECTIVE: To establish the level of interest in acupuncture as a treatment option for non-cardiac chest pain and to identify the factors associated with this interest. BACKGROUND: Non-cardiac chest pain is known to be a prevalent condition in the general population. Treatment options are limited. Given that acupuncture has a potential role in the treatment of chronic pain, this study was designed to establish the levels of interest in acupuncture among people with continuing non-cardiac chest pain. METHODS: This small study formed part of a larger retrospective cohort study, and was conducted with all 235 people who were given a diagnosis of non-cardiac chest pain at the Rapid Access Chest Pain Unit in York within a 14 month period. We collected data on whether people continued to experience chest pain, and if so, whether they had considered, or would consider, acupuncture as a treatment. We used ordinal logistic regression to investigate potential covariates, including sex and age, that might be associated with this interest. RESULTS: In total, 161 (69%) participants returned questionnaires, 75 (47%) of whom were experiencing continued chest pain with a median duration of 5.4 months. Of these participants, 42% reported that they would consider acupuncture, 36% reported that they would not, and 22% did not know. In the ordinal regression model, we found no covariates significantly associated with the strength of participants' interest in acupuncture. CONCLUSION: People with continuing non-cardiac chest pain after attending a Rapid Access Chest Pain Unit have shown considerable interest in acupuncture as a primary care treatment option.

Acupunct Med. 2007 Jun;25(1-2):18-21.

Source PubMed


Two Styles of Acupuncture for Treating Painful Diabetic Neuropathy

Ahn AC, Bennani T, Freeman R, Hamdy O, Kaptchuk TJ.

In a pilot study, we evaluated the clinical and mechanistic effects of two styles of acupuncture, Traditional Chinese Medicine (TCM) and Japanese acupuncture, for the treatment of painful diabetic neuropathy. Out of seven patients enrolled, three received Traditional Chinese acupuncture while four received Japanese style acupuncture. Treatments were delivered once a week for 10 weeks. Acupuncturists were permitted to select the needle interventions. Substantial differences in diagnostic techniques, choice of acupuncture points, and needle manipulation were observed between TCM and Japanese acupuncturists. Clinically, patients allocated to Japanese acupuncture reported decreased neuropathy-associated pain according to the daily pain severity score, while the group allocated to the TCM acupuncture reported minimal effects. Both acupuncture styles, however, lowered pain according to the McGill Short Form Pain Score. The TCM style improved nerve sensation according to quantitative sensory testing while the Japanese style had a more equivocal effect. No evident changes were observed in glucose control or heart rate variability in either group.

Acupunct Med. 2007 Jun;25(1-2):11-7.

Source: PubMed


Investigation of the Effects of Chinese Medicine on Fibroblast Viability: Implications in Wound Healing

Lau TW, et al. Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

Diabetes mellitus has been a clinical problem for hundreds of years. Over 194 million people suffer from this disease worldwide. Improper control of diabetes may result in diabetic foot ulcer or even amputation. Granulation formation is an important issue essential for ulcer healing. The CRL-7522 fibroblast cell line and primary fibroblasts from a diabetic foot ulcer patient were used to model the wound healing enhancing activities of two clinically efficacious Chinese herbal formulae, Formula 1 (F1) and Formula 2 (F2) and their component herbs. Results showed that the two formulae and four of their component herbs, Radix Astragali, Radix Rehmanniae, Rhizoma Alismatis and Rhizoma Atractylodis Macrocephalae significantly enhanced CRL-7522 cell viability. However, these component herbs showed compromised effects on the viability of primary fibroblasts cultured from the ulcerous tissue of a diabetic patient. Interestingly, F1 and F2 enhanced the viability of primary cultured fibroblasts from the diabetic patient even in the face of insulin resistance. These results further support the previously reported clinical efficacies of the two formulae on healing diabetic foot ulcers. Copyright (c) 2007 John Wiley & Sons, Ltd.

Phytother Res. 2007 Jun 22;

Source: PubMed


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